منابع مشابه
Kidney Cortex Tubules
Triacylglycerol metabolism has been studied in kidney cortex tubules from starved rats, prepared by collagenase treatment. Triacylglycerol was determined by a newly developed fully enzymic method. Incubation of tubules in the absence of fatty acids led to a decrease of endogenous triacylglycerol by about 50% in 1 h. Addition of albuminbound oleate or palmitate resulted in a steady increase of t...
متن کاملKidney Proximal Tubules
The aim of this study was to evaluate the role of the kidney in mediating the signals involved in adaptive changes in luminal Na+/H+ exchange and basolateral Na+:HCOcotransport systems in metabolic acidosis. Proximal tubular suspensions were prepared from rabbit kidney cortex and incubated in acidic (A) or control (C) media (pH 6.9 vs 7.4, 5% C02) for 2 h. Brush border membrane (BBM) and basola...
متن کاملProgress in microelectrode techniques for kidney tubules.
Altlhoughi microelectrocle measurements lhave caused a good deal of confusion in the investigation of renal electrolyte transport (for literature see Ref. 4), we cannot do witlhout them. Knowledge of the electrical potential steps, whiclh the ions have to pass (luring their reabsorption, is indispensable for understanding the transport meclhanisms involved. Hence the development of more reliabl...
متن کاملBioengineered kidney tubules efficiently excrete uremic toxins
The development of a biotechnological platform for the removal of waste products (e.g. uremic toxins), often bound to proteins in plasma, is a prerequisite to improve current treatment modalities for patients suffering from end stage renal disease (ESRD). Here, we present a newly designed bioengineered renal tubule capable of active uremic toxin secretion through the concerted action of essenti...
متن کاملSignificant water absorption goes paracellular in kidney proximal tubules.
IT HAD BEEN A FUNDAMENTAL dispute for several decades, whether water passes epithelia such as kidney proximal tubule or small intestine along the transcellular, paracellular, or both pathways. By discovery of the transmembranal aquaporin water channels (AQP), the molecular basis of the transcellular pathway was uncovered (1), but the molecular basis of the tight junctional pathway was not resol...
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ژورنال
عنوان ژورنال: Current Opinion in Nephrology and Hypertension
سال: 2016
ISSN: 1062-4821
DOI: 10.1097/mnh.0000000000000218